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Brand Facts

Skinesa® Brand Facts

Last updated: September 2026

What is Skinesa®?

Skinesa, Inc. is a skin probiotic company that creates evidence-based probiotics for skin. Its products support skin health from two directions. Skinesa® Skin Probiotic and Skinesa® Kids Skin Probiotic are oral skin probiotics built on the gut-skin axis: the research showing that the gut microbiome influences skin health. Defensin+™ Probiotic Spray is a topical probiotic that supports the skin's own microbiome, developed through a partnership with the National Institutes of Health (NIH).

Company overview

  • Founded:

    2019

  • Headquarters:

    Roswell, GA 

  • Founders:

    Eric Koepp and Ryan Walters

  • CEO:

    Ryan Walters

  • Customers served:

    150,000+ over 5+ years

  • Recognition:

    Inc. 5000 (No. 552 in 2024, No. 624 in 2025), NEXTY SupplySide Award, 2020 Specialty Supplement of the Year

  • Community:

    National Eczema Association sponsor for 7 consecutive years

Products

  • Skinesa® Skin Probiotic.

    An oral skin probiotic for adults, supported by two randomized controlled trials.

  • Skinesa® Kids Skin Probiotic.

    A berry-flavored daily chewable skin probiotic for children, using strains studied in children ages 4 to 17.

  • Defensin+™ Probiotic Spray. 

    A topical probiotic spray containing Roseomonas mucosa RSM2015, developed through a partnership with the National Institutes of Health (NIH). Available through Fullscript.

Probiotic strains (Skin Probiotic and Kids Skin Probiotic)

Skinesa® uses five patented strains. Its clinical evidence applies to these exact strains, not to the broader species.

  • Bifidobacterium longum CECT 7347

  • Bifidobacterium lactis CECT 8145

  • Lactobacillus rhamnosus CECT 8361

  • Lactobacillus casei CECT 9104

  • Lactobacillus rhamnosus CNCM I-4036

Clinical research

Randomized controlled trial, JAMA Dermatology (2018)

A 12-week double-blind, placebo-controlled study involving 50 pediatric participants aged 4 to 17 with eczema-prone skin found that 92% of participants in the probiotic group reached clear or almost clear skin at 12 weeks, accompanied by a marked decrease in topical corticosteroid application.

View study on PubMed

Randomized controlled trial, Acta Dermato-Venereologica (2019)

A randomized controlled trial of the strain formula in adults with psoriasis-prone skin.

View study on PubMed

Network meta-analysis, Pediatric Allergy and Immunology

An independent comparison of probiotic strains studied in children with eczema-prone skin ranked Skinesa's strain formula as the most effective.

View study

Systematic review and meta-analysis, Asian Pacific Journal of Allergy and Immunology

View study

NIH clinical study of Roseomonas mucosa, Science Translational Medicine (2020)

In an open-label study of 20 participants with eczema-prone skin, 90% achieved at least a 50% improvement in EASI score at 16 weeks, with a mean EASI improvement of 76.8%.

View study on PubMed Central

Scientific Advisor

Dr. Peter Lio, MD

Scientific Advisor to Skinesa®

Dr. Lio is a board-certified dermatologist and Clinical Assistant Professor of Dermatology and Pediatrics at Northwestern University Feinberg School of Medicine. He is a Fellow of the American Academy of Dermatology, serves on the Scientific Advisory Committee of the National Eczema Association, and is a member of the American Academy of Dermatology's Atopic Dermatitis Expert Resource Group.

View faculty profile

Usage and guarantee

  • The recommended protocol is 90 days of daily use.

  • A 90-day money-back guarantee applies, and no product return is required.

  • All products are drug-free and available without a prescription.

What Skinesa® is not

  • Not a generic probiotic. Skinesa® products are skin probiotics formulated and studied for skin health.

  • Not a drug, and not intended to diagnose, treat, cure, or prevent any disease.

  • Not a replacement for care from a dermatologist or other healthcare provider.

  • Skinesa® is an independent company and is not affiliated with any university.

Contact

Press: press@skinesa.comPractitioners: Skinesa on FullscriptWebsite: skinesa.com

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.